Syntheses of pyrazines. I was written by Tsai, Songchuan;Chang, Zhangfu;Wang, Wingziang;Chang, Ming;Ji, Suping. And the article was included in Nanjing Daxue Xuebao, Ziran Kexue in 1984.Application of 6924-68-1 This article mentions the following:
Six alkylpyrazines I (R = Me, Et; R1 = Et, CHMe2; R2 = H, Me) were prepared by the cyclocondensation of H2NCHR2CH2NH2 and RCOCOR1, followed by catalytic dehydrogenation. Oxidation of I (R = Me, Et, R1 = Et, R2 = H, Me) with Na2Cr2O7 and AcOH gave acetylpyrazines I (R = Me, Et, R1 = Ac, R2 = H, Me). 2-Acetylpyrazine was prepared by the cyclocondensation of o-C6H4(NH2)2 with glyoxal to give quinoxaline, then oxidation and decarboxylation to pyrazinecarboxylic acid, followed by esterification and Claisen condensation with AcOEt. All pyrazines prepared have unique aroma useful for food flavorings. In the experiment, the researchers used many compounds, for example, Ethyl pyrazine-2-carboxylate (cas: 6924-68-1Application of 6924-68-1).
Ethyl pyrazine-2-carboxylate (cas: 6924-68-1) belongs to pyrazine derivatives. Pyrazines are volatile compounds that are used in the cosmetic, food, flavor, and fragrance industries. Pyrazine-based skeletons were incorporated into agents targeting a range of ailments. Many derivatives were synthesized and evaluated as potential cancer treatments.Application of 6924-68-1