Identification of hydroxymethylpyrazines using mass spectrometry was written by Bohman, Bjoern;Flematti, Gavin R.;Barrow, Russell A.. And the article was included in Journal of Mass Spectrometry in 2015.Quality Control of (3,5,6-Trimethylpyrazin-2-yl)methanol This article mentions the following:
Pyrazines are well-known natural products that are present in bacterial odors and food flavoring agents and are used as insect pheromones. Recently, a number of hydroxymethylpyrazines have been identified as thynnine wasp pheromones and orchid semiochems. that are essential for pollination in sexually deceptive plants. These compounds are present in low amounts in complex blends, making GC-MS (including high-resolution techniques) the method of choice for their structure elucidation. We report the EI mass spectra for 14 representative compounds and have found that based on characteristic fragmentations, it is possible to distinguish between different positional isomers of hydroxymethylpyrazines. The presence or absence of either [M – 17]+, [M – 18]+璺?/sup> or [M – 19]+ fragment species provides characteristic information to allow the distinction between the different isomers. Considering the importance of pyrazines as a group of bioactive natural products, and the recent findings of biol. activity for hydroxymethylpyrazines, our results presented here will aid the identification of these compounds in other biol. systems. Copyright 婕?2015 John Wiley & Sons, Ltd. In the experiment, the researchers used many compounds, for example, (3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3Quality Control of (3,5,6-Trimethylpyrazin-2-yl)methanol).
(3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3) belongs to pyrazine derivatives. Pyrazine is a symmetrical molecule with point group D2h. Pyrazine is less basic than pyridine, pyridazine and pyrimidine. Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anion and decrease nitric oxide production in human Granulocytes.Quality Control of (3,5,6-Trimethylpyrazin-2-yl)methanol