Synthesis of tetramethylpyrazine metabolites was written by Liu, Xinyong;Ge, Weiying;Xu, Lijun;Zhang, Junren;Wang, Haiyan;Pan, Shuju. And the article was included in Shandong Yike Daxue Xuebao in 1997.COA of Formula: C8H12N2O This article mentions the following:
2-Acetoxylmethyl-3,5,6-trimethylpyrazine, 3,5,6-trimethylpyrazine methanol and 3,5,6-trimethylpyrazine formic acid were prepared from tetramethylpyrazine oxidation The alc. and the acid were tested active in lowering both cholesterol and LDL level in rabbit. In the experiment, the researchers used many compounds, for example, (3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3COA of Formula: C8H12N2O).
(3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3) belongs to pyrazine derivatives. Pyrazine heterocycles and their benzo derivatives possess many interesting properties, including chemical reactivity profiles, and have diverse applications in total synthesis, medicine, chemical biology, materials, dyes, and imaging. Pyrazines undergo nearly all of the same reactions as pyrimidines, from nucleophilic substitution (SNAr) to palladium-catalyzed cross coupling reactions.COA of Formula: C8H12N2O