Synthesis of tetramethylpyrazine derivatives by Mitsunobu reaction was written by Wang, Hui-ying;Sun, Ping-hua;Chen, Wei-min. And the article was included in Hecheng Huaxue in 2011.Application of 75907-74-3 This article mentions the following:
Three tetramethylpyrazine derivatives I(R = H, MeO), and II in yields of 87%∼92% were synthesized by Mitsunobu reaction from tetramethylpyrazine. The structures were characterized by 1H NMR, 13C NMR and ESI-MS. In the experiment, the researchers used many compounds, for example, (3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3Application of 75907-74-3).
(3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3) belongs to pyrazine derivatives. Pyrazine heterocycles and their benzo derivatives possess many interesting properties, including chemical reactivity profiles, and have diverse applications in total synthesis, medicine, chemical biology, materials, dyes, and imaging. Pyrazine heterocycles and their benzo derivatives possess many interesting properties, including chemical reactivity profiles, and have diverse applications in total synthesis, medicine, chemical biology, materials, dyes, and imaging.Application of 75907-74-3