Hydrophobicity parameters determined by reversed-phase liquid chromatography. IV. Shortcoming of log KW approach for prediction of log P of pyrazines was written by Yamagami, Chisako;Takao, Narao. And the article was included in Chemistry Express in 1991.Related Products of 6924-68-1 This article mentions the following:
The capacity factors of monosubstituted pyrazines on a C18-modified column were measured. The observed and extrapolated log kW (capacity factor in 100% water) values were compared with log P. The results suggested that the conventional log kW approach would not be applicable in the prediction of the log P value of polar solutes. In the experiment, the researchers used many compounds, for example, Ethyl pyrazine-2-carboxylate (cas: 6924-68-1Related Products of 6924-68-1).
Ethyl pyrazine-2-carboxylate (cas: 6924-68-1) belongs to pyrazine derivatives. Pyrazines are part of several biologically active polycyclic compounds; examples are quinoxalines, phenazines; and the bio-luminescent natural products pteridines, flavins, and their derivatives. Pyrazine-based skeletons were incorporated into agents targeting a range of ailments. Many derivatives were synthesized and evaluated as potential cancer treatments.Related Products of 6924-68-1