Reduction of azanaphthalenes by sodium borohydride in trifluoroacetic acid was written by Bugle, Robert C.;Osteryoung, Robert A.. And the article was included in Journal of Organic Chemistry in 1979.Category: pyrazines This article mentions the following:
Azanaphthalenes were reduced in high yield to the corresponding amines by tris(trifluoroacetoxy)borohydride. The pyrazine ring can be preferentially reduced within a mixed heteroaromatic nucleus, resulting in the regiospecific and clean reduction of many azanaphthalenes. A convenient one-step preparation of both tetrahydropteridines I and II is discussed, in addition to the preparation of 1,2,3,4-tetrahydroquinoxaline. In the experiment, the researchers used many compounds, for example, Pyrido[2,3-b]pyrazine (cas: 322-46-3Category: pyrazines).
Pyrido[2,3-b]pyrazine (cas: 322-46-3) belongs to pyrazine derivatives. Pyrazines are part of several biologically active polycyclic compounds; examples are quinoxalines, phenazines; and the bio-luminescent natural products pteridines, flavins, and their derivatives. A large number of pyrazine derivatives are known for their antitumor, antibiotic, anticonvulsant, antituberculosis, and diuretic activities.Category: pyrazines