Cinnolines. IV. Quaternization of 4-amino-6-chloro- and 6-chloro-4-phenoxycinnoline was written by Ames, D. E.. And the article was included in Journal of the Chemical Society in 1964.Name: 5-Aminopyrazine-2-carboxamide This article mentions the following:
The work of Simpson (CA 42, 2978e) on the quaternization of 4-amino-6-chlorocinnoline (I) has been reexamined, and alkylation is shown to occur at N-1 and N-2 on the basis of revised structures for the methylation products of 6-chloro-4-hydroxycinnoline. 6-Chloro-4-phenoxycinnoline, however, appears to form a methiodide only by reaction at N-2. In the experiment, the researchers used many compounds, for example, 5-Aminopyrazine-2-carboxamide (cas: 89323-09-1Name: 5-Aminopyrazine-2-carboxamide).
5-Aminopyrazine-2-carboxamide (cas: 89323-09-1) belongs to pyrazine derivatives. Pyrazines are part of several biologically active polycyclic compounds; examples are quinoxalines, phenazines; and the bio-luminescent natural products pteridines, flavins, and their derivatives. Substituted pyrazines have been found as subunits of multiple synthetically constructed therapeutic agents, as well as several natural products.Name: 5-Aminopyrazine-2-carboxamide