Vicarious nucleophilic substitution of hydrogen, bisannulation and competitive reactions of α-haloalkyl carbanions with bicyclic azaaromatic compounds was written by Makosza, Mieczyslaw;Golinski, Jerzy;Ostrowski, Stanislaw;Rykowski, Andrzej;Sahasrabudhe, Arvind B.. And the article was included in Chemische Berichte in 1991.HPLC of Formula: 322-46-3 This article mentions the following:
Carbanions of RR1CHSO2R2 (I; R = Cl, R1 = H, Me, R2 = NMe2, Ph, CMe3, morpholino, tolyl; R = Br, R1 = H, R2 = tolyl) react with bicyclic heteroaromatic compounds (quinoxalines, naphthyridines, and 5-azaquinoxalines) according to 2 general pathways: vicarious nucleophilic substitution (VNS) of hydrogen and/or bisannulation. In some cases other competitive reactions are observed Factors governing the direction of these reactions are discussed in terms of the charge distribution in the anionic σ adducts and the reaction conditions. For example reaction of quinoxaline and quinoxaline N-oxide with I (R = Cl, R1 = H, R2 = Ph) gave bisazirinoquinoxaline II and VNS product III resp. In the experiment, the researchers used many compounds, for example, Pyrido[2,3-b]pyrazine (cas: 322-46-3HPLC of Formula: 322-46-3).
Pyrido[2,3-b]pyrazine (cas: 322-46-3) belongs to pyrazine derivatives. Pyrazine is a symmetrical molecule with point group D2h. Pyrazine is less basic than pyridine, pyridazine and pyrimidine. Pyrazines are chemical compounds (technically called âmethoxypyrazinesâ? found in grape skin and stems that are responsible for many âgreenâ?flavors in wine. Levels of pyrazines are dependent on viticultural practices, climate, and grape variety.HPLC of Formula: 322-46-3