Synthesis of 4-aryl(hetaryl)pyrazolo[1,5-a]pyrazines by palladium-catalyzed Suzuki-Miyaura cross coupling was written by Hrynyshyn, Yevhenii V.;Musiychuk, Anna R.;Tsizorik, Nazar M.;Bol’but, Andriy V.;Vovk, Mikhailo V.. And the article was included in Chemistry of Heterocyclic Compounds in 2019.Product Details of 1314920-48-3 The following contents are mentioned in the article:
Synthesis of 4-aryl(hetaryl)pyrazolo[1,5-a]pyrazines by the Suzuki-Miyaura cross coupling reaction of 4-bromopyrazolo[1,5-a]pyrazines with aryl(hetaryl)boronic acids in the presence of catalytic amounts of Pd(dppf)Cl2·CH2Cl2 and an excess of Cs2CO3 in the MeCN-H2O, 9:1 solvent system is discussed. This study involved multiple reactions and reactants, such as 2-Methylpyrazolo[1,5-a]pyrazin-4(5H)-one (cas: 1314920-48-3Product Details of 1314920-48-3).
2-Methylpyrazolo[1,5-a]pyrazin-4(5H)-one (cas: 1314920-48-3) belongs to pyrazine derivatives. Pyrazine heterocycles and their benzo derivatives possess many interesting properties, including chemical reactivity profiles, and have diverse applications in total synthesis, medicine, chemical biology, materials, dyes, and imaging. Substituted pyrazines have been found as subunits of multiple synthetically constructed therapeutic agents, as well as several natural products.Product Details of 1314920-48-3