Synthesis of 8H-pyrazolo[5′,1′:3,4]pyrazino[2,1-b]quinazolin-8-ones was written by Hrynyshyn, Yevhenii V.;Tsizorik, Nazar M.;Musiychuk, Anna R.;Bol’but, Andriy V.;Vovk, Mykhailo V.. And the article was included in Chemistry of Heterocyclic Compounds in 2017.COA of Formula: C7H7N3O The following contents are mentioned in the article:
4-Chloropyrazolo[1,5-a]pyrazines reacted with anthranilic acids forming 8H-pyrazolo[5′,1′:3,4]pyrazino[2,1-b]quinazolin-8-ones I (R1 = H, CF3, Me, NO2; R2 = H, OMe; R3 = H, Me, OMe) representing a new heterocyclic system. This study involved multiple reactions and reactants, such as 2-Methylpyrazolo[1,5-a]pyrazin-4(5H)-one (cas: 1314920-48-3COA of Formula: C7H7N3O).
2-Methylpyrazolo[1,5-a]pyrazin-4(5H)-one (cas: 1314920-48-3) belongs to pyrazine derivatives. Pyrazinesare six-membered aromatic heterocyclic organic compounds with two nitrogen atoms at 1,4-positions. Pyrazine is a weaker base (pKb = 13.4) than pyridine (pKb = 8.8), pyrimidine (pKb = 12.7). Pyrazine-based skeletons were incorporated into agents targeting a range of ailments. Many derivatives were synthesized and evaluated as potential cancer treatments.COA of Formula: C7H7N3O