Putta, V. P. Rama Kishore published the artcileA metal- and base-free domino protocol for the synthesis of 1,3-benzoselenazines, 1,3-benzothiazines and related scaffolds, Recommanded Product: Pyrazine-2-carbothioamide, the publication is Organic & Biomolecular Chemistry (2019), 17(9), 2516-2528, database is CAplus and MEDLINE.
Efficient protocols have been described for the synthesis of 1,3-benzoselenazines, 1,3-benzothiazines, 2-arylthiazin-4-ones and diaryl[b,f][1,5]diazocine-6,12(5H,11H)-diones. These transformations were successfully driven towards product formation under mild acid catalyzed reaction conditions at room temperature using 2-aminoaryl/hetero-aryl alkyl alcs. and amides as substrates. The merits of the present methods also rely on the easy access of rarely explored bioactive scaffolds like 1,3-benzoselenazine derivatives, for which well-documented methods are rarely known in the literature. A broad range of substrates with both electron-rich and electron-deficient groups were well-tolerated under the developed conditions to furnish the desired products in yields up to 98%. The scope of the devised method was not only restricted to the synthesis of 1,3-benzoselenazines, but it was further extended towards the synthesis of 1,3-benzothiazines, 1,3-benzothiazinones and the corresponding eight-membered N-heterocycles such as diaryl[b,f][1,5]diazocine-6,12(5H,11H)-diones.
Organic & Biomolecular Chemistry published new progress about 4604-72-2. 4604-72-2 belongs to pyrazines, auxiliary class Pyrazine,Amine,Amide, name is Pyrazine-2-carbothioamide, and the molecular formula is C5H5N3S, Recommanded Product: Pyrazine-2-carbothioamide.
Referemce:
https://en.wikipedia.org/wiki/Pyrazine,
Pyrazine | C4H4N2 – PubChem