Daniel, Matthieu published the artcileIntramolecular Metal-Free N-N Bond Formation with Heteroaromatic Amines: Mild Access to Fused-Triazapentalene Derivatives, Application of 2-Chloro-5-(trifluoromethyl)pyrazine, the main research area is triazapentalene preparation; heteroaromatic amine intramol cyclization bond formation; N−N bond formation; heteroaromatic amines; hypervalent compounds; iodine; triazapentalene derivatives.
Formation of N-N bonds may offer an original approach to various nitrogen-containing heterocycles I (R = CH, N; R1 = CH, N, C-CF3, C-OCH3; R2 = CH, N, C-CF3, C-Br, C-CN; R3 = CH, N, C-CF3; R4 = H, CH3; R5 = H, OCH3, CH3, CF3, Br; R6 = H, CH3) with numerous applications. For this purpose, it is found that readily available heteroaromatic amines II are appropriate substrates for providing an efficient and innovative approach for the formation of N-N bonds in the presence of iodine (III) reagent in very mild conditions. This method makes it possible to synthesize nitrogen rich triazapentalene derivatives exhibiting fluorescent properties, inaccessible with existing approaches.
Chemistry – A European Journal published new progress about Absorption. 799557-87-2 belongs to class pyrazines, name is 2-Chloro-5-(trifluoromethyl)pyrazine, and the molecular formula is C5H2ClF3N2, Application of 2-Chloro-5-(trifluoromethyl)pyrazine.