Sato, Nobuhiro published the artcileStudies on pyrazines. 13. Chlorination of 1-hydroxy-2(1H)-pyrazinones with phosphoryl chloride. Formation of 2,5-dichloro-3-phenylpyrazine from 1-hydroxy-3-phenyl-2(1H)-pyrazinone, COA of Formula: C5H5ClN2O, the main research area is hydroxyphenylpyrazinone chlorination; pyrazinone hydroxyphenyl chlorination.
The chlorination of 1-hydroxy-3-phenyl-2(1H)-pyrazinone (I) with POCl3 proceeded to 5-chloro-3-phenyl-2(1H)-pyrazinone or 2,5-dichloro-3-phenylpyrazine on heating to elevated temperatures To define the mechanism of the novel formation, reactions of the parent or methyl-substituted 1-hydroxy-2(1H)-pyrazinones with the same reagent were investigated.
Journal of Heterocyclic Chemistry published new progress about Chlorination. 89283-33-0 belongs to class pyrazines, name is 3-Chloro-5-methylpyrazin-2(1H)-one, and the molecular formula is C5H5ClN2O, COA of Formula: C5H5ClN2O.