Lin, Daniel published the artcileVisible Light-Mediated Metal-Free Chlorodifluoromethylation of Arenes and Heteroarenes by a Hypervalent Iodine EDA Complex, Synthetic Route of 14667-55-1, the main research area is arene heteroarene chlorodifluoromethylation visible light hypervalent iodine EDA complex.
A novel EDA complex comprised of a bis(chlorodifluoroacetoxy)iodoarene and 1,3,5-trimethoxybenzene is described, which enables the direct radical C(sp2)-H chlorodifluoromethylation of arenes and heteroarenes under monochromatic visible-light irradiation The procedure is mild, operationally simple, and utilizes com. available reagents. The developed conditions demonstrate compatibility with a host of commonly encountered functionalities and biol. relevant scaffolds, while showcasing the post-functionalization capabilities of the -CF2Cl moiety. Various mechanistic studies were performed to explore the EDA complex and radical generation pathway.
European Journal of Organic Chemistry published new progress about C-H bond activation. 14667-55-1 belongs to class pyrazines, name is 2,3,5-Trimethylpyrazine, and the molecular formula is C7H10N2, Synthetic Route of 14667-55-1.