Liao, Ke published the artcileCatalytic cleavage and functionalization of bulky and inert Csp3-Csp3 bonds via a relayed proton-coupled electron transfer strategy, Safety of 2,3,5-Trimethylpyrazine, the main research area is alc radicalophile acridinium tetrafluoroborate regioselective photochem bond cleavage functionalization.
The direct, photoredox cleavage of hindered Csp3-Csp3 bonds of alcs. under neutral conditions was described. A relayed proton-coupled electron transfer (PCET) strategy was employed that overcame the previous requirement of a Bronsted base. Heavily branched alcs. with a high oxidation potential (Eox1/2 > +2 V vs. SCE) were cleaved and functionalized with remarkable efficiency and versatility. A simple, non-substituted Ph group can promote a relayed PCET process to deliver primary, secondary, and tertiary alkyl radicals under neutral conditions.
Cell Reports Physical Science published new progress about Bond cleavage catalysts (photochem., regioselective). 14667-55-1 belongs to class pyrazines, name is 2,3,5-Trimethylpyrazine, and the molecular formula is C7H10N2, Safety of 2,3,5-Trimethylpyrazine.