Sawa, Tadaki et al. published their patent in 2013 |CAS: 87486-34-8

The Article related to benzoxadiazole fluorescent probe kinase inhibitor screening, Biochemical Methods: Spectral and Related Methods and other aspects.HPLC of Formula: 87486-34-8

On May 30, 2013, Sawa, Tadaki; Kawabata, Wataru; Asami, Saiko published a patent.HPLC of Formula: 87486-34-8 The title of the patent was Novel fluorescent probe, and kinase inhibitor novel screening method. And the patent contained the following:

A novel benzoxadiazole fluorescent probe shown by the formula (I) is provided, which enables to screen a kinase inhibitor. In (I), Z represents a compound possessing a kinase inhibitory activity; L represents an optionally bound or substituted amino group, a carbonyl group, an optionally substituted hydrocarbon group, an optionally substituted alkylcarbamoyl group, an optionally substituted acylamino group, a sulfide group, or an optionally substituted alkoxy group; X represents an optionally bound or substituted amino group, an optionally substituted hydrazino group, or a thiocarbonyl amino group; and R1 represents a nitro group, or a dimethylsulfamoyl group. The experimental process involved the reaction of 3,5-Dibromo-1-methylpyrazin-2(1H)-one(cas: 87486-34-8).HPLC of Formula: 87486-34-8

The Article related to benzoxadiazole fluorescent probe kinase inhibitor screening, Biochemical Methods: Spectral and Related Methods and other aspects.HPLC of Formula: 87486-34-8

Referemce:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem