Nishihara, Ryo et al. published their research in Bioconjugate Chemistry in 2020 |CAS: 55779-48-1

The Article related to coelenterazine analog serum albumin bioluminescence, Biochemical Methods: Spectral and Related Methods and other aspects.Category: pyrazines

On December 16, 2020, Nishihara, Ryo; Niwa, Kazuki; Tomita, Tatsunosuke; Kurita, Ryoji published an article.Category: pyrazines The title of the article was Coelenterazine Analogue with Human Serum Albumin-Specific Bioluminescence. And the article contained the following:

A synthetic luciferin comprising an imidazopyrazinone core, named HuLumino1, was designed to generate specific bioluminescence with human serum albumin (HSA) in real serum samples. HuLumino1 was developed by attaching a methoxy-terminated alkyl chain to C-6 of coelenterazine and by eliminating a benzyl group at C-8. HSA levels were quantified within 5% error margins of an ELISA without the need for any sample pretreatments because of the high specificity of HuLumino1. The experimental process involved the reaction of 8-Benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one(cas: 55779-48-1).Category: pyrazines

The Article related to coelenterazine analog serum albumin bioluminescence, Biochemical Methods: Spectral and Related Methods and other aspects.Category: pyrazines

Referemce:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem