On December 31, 2020, Tessler, Michael; Gaffney, Jean P.; Oliveira, Anderson G.; Guarnaccia, Andrew; Dobi, Krista C.; Gujarati, Nehaben A.; Galbraith, Moira; Mirza, Jeremy D.; Sparks, John S.; Pieribone, Vincent A.; Wood, Robert J.; Gruber, David F. published an article.Related Products of 55779-48-1 The title of the article was A putative chordate luciferase from a cosmopolitan tunicate indicates convergent bioluminescence evolution across phyla. And the article contained the following:
Pyrosomes are tunicates in the phylum Chordata, which also contains vertebrates. Their gigantic blooms play important ecol. and biogeochem. roles in oceans. Pyrosoma, meaning “fire-body”, derives from their brilliant bioluminescence. The biochem. of this light production is unknown, but has been hypothesized to be bacterial in origin. We found that mixing coelenterazine-a eukaryote-specific luciferin-with Pyrosoma atlanticum homogenate produced light. To identify the bioluminescent machinery, we sequenced P. atlanticum transcriptomes and found a sequence match to a cnidarian luciferase (RLuc). We expressed this novel luciferase (PyroLuc) and, combined with coelenterazine, it produced light. A similar gene was recently predicted from a bioluminescent brittle star, indicating that RLuc-like luciferases may have evolved convergently from homologous dehalogenases across phyla (Cnidaria, Echinodermata, and Chordata). This report indicates that a widespread gene may be able to functionally converge, resulting in bioluminescence across animal phyla, and describes and characterizes the first putative chordate luciferase. The experimental process involved the reaction of 8-Benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one(cas: 55779-48-1).Related Products of 55779-48-1
The Article related to pyrosoma atlanticum vertebrates transcriptomes bioluminescence bacteria, Nonmammalian Biochemistry: Classical Genetics and Phylogeny and other aspects.Related Products of 55779-48-1