On December 18, 2020, Bessho-Uehara, Manabu; Huang, Wentao; Patry, Wyatt L.; Browne, William E.; Weng, Jing-Ke; Haddock, Steven H. D. published an article.Formula: C26H21N3O3 The title of the article was Evidence for de novo Biosynthesis of the Luminous Substrate Coelenterazine in Ctenophores. And the article contained the following:
Coelenterazine is a key substrate involved in marine bioluminescence which is used for light-production by at least nine phyla. Some luminous animals, such as the hydromedusa Aequorea, lack the ability to produce coelenterazine endogenously and instead depend on dietary sources. Little is known about the source organisms or the metabolic process of coelenterazine biosynthesis. Here, we present evidence that ctenophores are both producers and suppliers of coelenterazine in marine ecosystems. Using biochem. assays and mass spectrometry analyses, we detected coelenterazine from cultured ctenophores fed with a non-luminous coelenterazine-free diet. We propose that ctenophores are an emerging model organism to study coelenterazine biosynthesis and the origins of bioluminescence. The experimental process involved the reaction of 8-Benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one(cas: 55779-48-1).Formula: C26H21N3O3
The Article related to beroe mnemiopsis bolinopsis pleurobrachia coelenterazine bioluminescence, biomolecules, biosynthesis, evolutionary developmental biology, evolutionary history, Microbial, Algal, and Fungal Biochemistry: Composition and Products and other aspects.Formula: C26H21N3O3