Coutant, Eloi P.; Goyard, Sophie; Hervin, Vincent; Gagnot, Glwadys; Baatallah, Racha; Jacob, Yves; Rose, Thierry; Janin, Yves L. published an article in 2019, the title of the article was Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties.Formula: C26H21N3O3 And the article contains the following content:
An original gram-scale synthesis of O-acetylated forms of coelenterazine, furimazine or hydroxy-bearing analogs of luciferins is described. The comparison over two hours of their bioluminescence, using the nanoKAZ/NanoLuc luciferase, provides remarkable insights useful for the selection of a substrate adapted for a given application. The experimental process involved the reaction of 8-Benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one(cas: 55779-48-1).Formula: C26H21N3O3
The Article related to luciferin coelenterazine preparation bioluminescence kinetics light absorption, luciferase inhibition kinetics luciferin, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Formula: C26H21N3O3