Zhang, Hua; Lai, Wei; Guan, Zhuo-Bin; Liao, Xiao-Jian; Zhao, Bing-Xin; Xu, Shi-Hai published the artcile< A new thiodiketopiperzaine from the marine sponge Tedania sp.>, Safety of (3S,8aS)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione, the main research area is diketopiperzaine isolation structure sponge; Sponge; Tedania sp.; thiodiketopiperzaine.
A new thiodiketopiperzaine, tedanizaine A (I), together with 6 known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of I was established by ECD calculation I was the 2nd example of thiodiketopiperazine bearing a thiazolidine unit. Cytotoxic activities of I were also evaluated.
Natural Product Research published new progress about Diketopiperazines Role: BSU (Biological Study, Unclassified), NPO (Natural Product Occurrence), PAC (Pharmacological Activity), PRP (Properties), PUR (Purification or Recovery), BIOL (Biological Study), OCCU (Occurrence), PREP (Preparation). 2873-36-1 belongs to class pyrazines, and the molecular formula is C11H18N2O2, Safety of (3S,8aS)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione.