《Novel condensation of 2,3-epoxybutanal with 2-aminopyridine and 2-aminopyrazine. Synthesis and stability of 3-(1-hydroxyethyl)imidazo[1,2-a]azines》 was written by Lumma, William C. Jr.; Springer, James P.. Formula: C8H7N3O And the article was included in Journal of Organic Chemistry on August 28 ,1981. The article conveys some information:
The title condensations gave azines I (X = CH, N) in 53 and 26% yield, resp. I (X = N) was oxidized to give 81% ketone II. I were not easily accessible by functionalization of the parent heterocycles due to facile decomposition of the latter. The crystal structure of II was determined After reading the article, we found that the author used 1-(Imidazo[1,2-a]pyrazin-3-yl)ethanone(cas: 78109-26-9Formula: C8H7N3O)
1-(Imidazo[1,2-a]pyrazin-3-yl)ethanone(cas: 78109-26-9) is a member of imidazole. Its exclusive structural characteristics with enviable electron-rich features are favorable for imidazole-based fused heterocycles to bind efficiently with an array of enzymes and receptors in biological systems through various weak interactions like hydrogen bonds, ion-dipole, cation-π, π-π stacking, coordination, Van der Waals forces, hydrophobic effects, etc., and therefore they demonstrate widespread bioactivities. Formula: C8H7N3O