Pyrazine is a heterocyclic aromatic organic compound with the chemical formula C4H4N2. It is a symmetrical molecule with point group D2h. Pyrazine is less basic than pyridine, pyridazine and pyrimidine. 22047-25-2, formula is C6H6N2O, Name is Acetylpyrazine. It is a deliquescent crystal or wax-like solid with a pungent, sweet, corn-like, nutty odour. Related Products of 22047-25-2.
Xu, Xiangchao;Ai, Yao;Wang, Rongzhou;Liu, Liping;Yang, Jiazhi;Li, Feng research published 《 Ruthenium-catalyzed acceptorless dehydrogenative coupling of o-aminobenzyl alcohols with ketones to quinolines in the presence of carbonate salt》, the research content is summarized as follows. A ruthenium complex bearing a functional 2,2′-bibenzimidazole ligand [(p-cymene)Ru(BiBzImH2)Cl][Cl] was designed, synthesized and found to be a general and highly efficient catalyst for the synthesis of quinolines I [R = H, Cl, Br; R1 = H, F, Cl, Me, OMe; R2 = t-Bu, cyclopropyl, Ph, pyrazin-2-yl, etc.; R3 = H, Me, Et] and 5,6-dihydrobenzo[c]acridine via acceptorless dehydrogenative coupling of o-aminobenzyl alcs. 2-NH2-4-R-5-R1-C6H2CH2OH with ketones R2C(O)CH2R3 and 1-tetralone in the presence of carbonate salt. It was confirmed that NH units in the ligand are crucial for catalytic activity. The application of this catalytic system for the scale-gram synthesis of biol. active mol. was also undertaken. Notably, this research exhibits new potential of metal-ligand bifunctional catalysts for acceptorless dehydrogenative reactions.
Related Products of 22047-25-2, 2-Acetylpyrazine has been identified as one of the volatile flavor constituents in popcorn, wheat and rye bread crust.
2-Acetylpyrazine, also known as 1-pyrazinylethanone or fema 3126, belongs to the class of organic compounds known as aryl alkyl ketones. These are ketones have the generic structure RC(=O)R’, where R = aryl group and R’=alkyl group. 2-Acetylpyrazine exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, 2-acetylpyrazine is primarily located in the cytoplasm. 2-Acetylpyrazine has a bitter, bread crust, and chip taste.
2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines.
2-Acetylpyrazine is a nitrogen containing compound that has been used in biological studies. 2-Acetylpyrazine has been shown to have inhibitory properties against the growth of prostate cancer cells and other cell lines. It also inhibits the production of fatty acids and epidermal growth factor, which are important for cellular proliferation. The inhibition is due to the photochemical properties of 2-acetylpyrazine, which cause the formation of reactive species that react with biological molecules. The reactive species may be generated by either a reaction mechanism or a reaction pathway that involve coordination geometry. 2-acetylpyrazine has also been used as a fluorescence probe for fatty acid detection in lipid bilayers and liposomes., 22047-25-2.