Golla, Ramesh team published research on Journal of Molecular Structure in 2020 | 22047-25-2

22047-25-2, 2-Acetylpyrazine has been identified as one of the volatile flavor constituents in popcorn, wheat and rye bread crust.
2-Acetylpyrazine, also known as 1-pyrazinylethanone or fema 3126, belongs to the class of organic compounds known as aryl alkyl ketones. These are ketones have the generic structure RC(=O)R’, where R = aryl group and R’=alkyl group. 2-Acetylpyrazine exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, 2-acetylpyrazine is primarily located in the cytoplasm. 2-Acetylpyrazine has a bitter, bread crust, and chip taste.
2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines.
2-Acetylpyrazine is a nitrogen containing compound that has been used in biological studies. 2-Acetylpyrazine has been shown to have inhibitory properties against the growth of prostate cancer cells and other cell lines. It also inhibits the production of fatty acids and epidermal growth factor, which are important for cellular proliferation. The inhibition is due to the photochemical properties of 2-acetylpyrazine, which cause the formation of reactive species that react with biological molecules. The reactive species may be generated by either a reaction mechanism or a reaction pathway that involve coordination geometry. 2-acetylpyrazine has also been used as a fluorescence probe for fatty acid detection in lipid bilayers and liposomes., COA of Formula: C6H6N2O

Pyrazine has the elements of symmetry for the point group D2h. It has three mutually perpendicular two-fold axes. 22047-25-2, formula is C6H6N2O, Name is Acetylpyrazine. It also has three mutually perpendicular planes of symmetry. As a result, pyrazine also has a centre of symmetry.. COA of Formula: C6H6N2O.

Golla, Ramesh;Kumar, P. Raghavendra;Suchethan, P. A.;Foro, Sabine;Nagaraju, G. research published 《 Synthesis, photophysical, electrochemical properties and crystal structures and Hirschfeld surface analysis of 4′-dimethoxyphenyl-(2,6-di-2-pyrazinyl) pyridines》, the research content is summarized as follows. Four new 4′-dimethoxyphenyl-(2,6-di-2-pyrazinyl) pyridines I [R = 2,3-(MeO)2C6H3, 2,4-(MeO)2C6H3, 2,5-(MeO)2C6H3, 3,4-(MeO)2C6H3] were synthesized by a facile one-pot method using 2-acetylpyrazine and n,n’-dimethoxybanzaldehydes. All compounds were characterized by 1H and 13C{1H} NMR, and FT-IR spectroscopy. The mol. structure of compounds I [R = 2,3-(MeO)2C6H3, 2,4-(MeO)2C6H3, 2,5-(MeO)2C6H3] was also confirmed by single crystal X-ray diffraction. There exists CH···N, CH···O and C···C aromatic stacking type of intermol. secondary interactions which resulted into supramol. structures in compounds I [R = 2,3-(MeO)2C6H3, 2,4-(MeO)2C6H3, 2,5-(MeO)2C6H3]. The Hirshfeld surface anal. was carried out for the confirmation of intermol. secondary interactions. The dihedral angles between substituted dimethoxyphenyl ring (B) and central pyridine (A) and pyrazine rings (C and D) are in the range of 33-45°. The photophys. properties were studied by UV-Visible and fluorescence spectroscopy and electrochem. properties by cyclic voltammetry. In the UV-Visible spectra, the compounds I [R = 2,3-(MeO)2C6H3, 2,4-(MeO)2C6H3, 2,5-(MeO)2C6H3, 3,4-(MeO)2C6H3] showed two strong bands at λmax, 236-238 and 284-293 nm attributed to the intramol. charge transfer (π-π*) transitions. When these compounds were excited at 350 nm observed emission bands at λem, 463, 511, 462, and 407 nm resp. The compounds I [R = 2,3-(MeO)2C6H3, 2,4-(MeO)2C6H3, 2,5-(MeO)2C6H3] were showed an oxidation peak, (Eox, 1.18, 1.57 and 1.25 V) but compound I [R = 3,4-(MeO)2C6H3] showed two oxidation peaks (Eox, 1.20 and 1.84 V). Astonishingly, only compound I [R = 2,5-(MeO)2C6H3] have shown a reduction peak at (Ered, 1.33 V) but there was no reduction peak in the other compounds This shows that the compound I [R = 2,5-(MeO)2C6H3] undergo reversible redox reaction.

22047-25-2, 2-Acetylpyrazine has been identified as one of the volatile flavor constituents in popcorn, wheat and rye bread crust.
2-Acetylpyrazine, also known as 1-pyrazinylethanone or fema 3126, belongs to the class of organic compounds known as aryl alkyl ketones. These are ketones have the generic structure RC(=O)R’, where R = aryl group and R’=alkyl group. 2-Acetylpyrazine exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, 2-acetylpyrazine is primarily located in the cytoplasm. 2-Acetylpyrazine has a bitter, bread crust, and chip taste.
2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines.
2-Acetylpyrazine is a nitrogen containing compound that has been used in biological studies. 2-Acetylpyrazine has been shown to have inhibitory properties against the growth of prostate cancer cells and other cell lines. It also inhibits the production of fatty acids and epidermal growth factor, which are important for cellular proliferation. The inhibition is due to the photochemical properties of 2-acetylpyrazine, which cause the formation of reactive species that react with biological molecules. The reactive species may be generated by either a reaction mechanism or a reaction pathway that involve coordination geometry. 2-acetylpyrazine has also been used as a fluorescence probe for fatty acid detection in lipid bilayers and liposomes., COA of Formula: C6H6N2O

Referemce:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem