Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. 22047-25-2, formula is C6H6N2O, Name is Acetylpyrazine. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anion and decrease nitric oxide production in human Granulocytes. COA of Formula: C6H6N2O.
Awantu, Angelbert F.;Ayimele, Godfred A.;Bankeu, Jean Jules K.;Nantia, Edouard A.;Fokou, Patrick V. T.;Boyom, Fabrice F.;Nfor, Emmanuel N.;Lenta, Bruno N.;Ngouela, Silvere A. research published 《 Synthesis, molecular structure, anti-plasmodial, antimicrobial and anti-oxidant screening of (E)-1-[2-(1-(pyrazin-2-yl)ethylidene)hydrazinyl]phthalazine and 1-[2-(1-(pyridin-2-yl)ethylidene)hydrazinyl]phthalazine》, the research content is summarized as follows. Two new hydralazine hydrochloride-derived Schiff bases: I [X = CH, N] were synthesized and partially characterized by spectroscopic and crystallog. methods including IR and X-ray. The single-crystal X-ray diffraction (SCXRD) anal. of compound I [X = CH] indicated that the hydralazine moiety of both ligands possesses the exocyclic C=N bond. Both compounds I were tested as antimicrobials and antiparasites. Compound I [X = CH] could be considered as slightly antiplasmodial and antibacterial agent. In effect, compound I [X = N] showed low antimicrobial activity against one bacterial strain with Min. Inhibitory Concentration (MIC) value of 250μg/mL while compound I [X = CH] showed very interesting activity against 18 out of 19 bacterial strains with MIC of 31.25 – 250μg/mL compared to the standard drug, amoxicillin. Compounds I showed higher reducing activity on ferric ions compared to vitamin C. On the other hand, compounds I showed as better reducing agents than vitamin C on ferric ions, while again, only the I [X = CH] showed slightly high inhibition of lipid peroxidation using vitamin C as standard Regarding their catalase activity, both compounds I showed concentration dependent effect, but vitamin C continued showing a higher stimulatory effect on the enzyme activity. Addnl., while compound I [X = N] showed less than 80% inhibition in the preliminary antiplasmodial assay and so was not considered for the dose-response studies, compound I [X = CH] displayed an inhibition percentage of 83.60% and 50% Inhibitory Concentration (IC50) value of 44.13μg/mL compared to the standard drug, artemisinin and was classified as slightly active.
COA of Formula: C6H6N2O, 2-Acetylpyrazine has been identified as one of the volatile flavor constituents in popcorn, wheat and rye bread crust.
2-Acetylpyrazine, also known as 1-pyrazinylethanone or fema 3126, belongs to the class of organic compounds known as aryl alkyl ketones. These are ketones have the generic structure RC(=O)R’, where R = aryl group and R’=alkyl group. 2-Acetylpyrazine exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, 2-acetylpyrazine is primarily located in the cytoplasm. 2-Acetylpyrazine has a bitter, bread crust, and chip taste.
2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines.
2-Acetylpyrazine is a nitrogen containing compound that has been used in biological studies. 2-Acetylpyrazine has been shown to have inhibitory properties against the growth of prostate cancer cells and other cell lines. It also inhibits the production of fatty acids and epidermal growth factor, which are important for cellular proliferation. The inhibition is due to the photochemical properties of 2-acetylpyrazine, which cause the formation of reactive species that react with biological molecules. The reactive species may be generated by either a reaction mechanism or a reaction pathway that involve coordination geometry. 2-acetylpyrazine has also been used as a fluorescence probe for fatty acid detection in lipid bilayers and liposomes., 22047-25-2.