In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A Two-Stage Iterative Process for the Synthesis of Poly-oxazoles, published in 2005-07-21, which mentions a compound: 118994-89-1, mainly applied to oxazole oligomer preparation, COA of Formula: C6H7NO3.
Methodol. has been developed to prepare bis-oxazoles via a two-stage iterative process. The sequence begins with C(2)-chlorination of a lithiated oxazole using hexachloroethane. Generation of the C(2)-C(4′) bond by SNAr substitution with TosMIC anion, followed by conversion to the heterocycle in a one-pot reaction with glyoxylic acid monohydrate, affords the desired bis-oxazole in good yield and purity. The two-stage process allows for efficient synthesis of a tris-oxazole and the iterative preparation of a tetra-oxazole.
After consulting a lot of data, we found that this compound(118994-89-1)COA of Formula: C6H7NO3 can be used in many types of reactions. And in most cases, this compound has more advantages.