Name: Ethyl oxazole-5-carboxylate. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Ethyl oxazole-5-carboxylate, is researched, Molecular C6H7NO3, CAS is 118994-89-1, about Copper-catalyzed diarylation of Se with aryl iodides and heterocycles. Author is Hu, Dehua; Liu, Miaochang; Wu, Huayue; Gao, Wenxia; Wu, Ge.
The regioselective copper-catalyzed three-component coupling reaction of electron-deficient heterocycles, like aryl-oxadiazoles/aryloxazoles/dimethyl-purine-diones, etc. with aryl iodides in presence of Se powder so as to yield corresponding diaryl-selenated heterocycles such as arylselanyl-aryl-oxadiazoles I [R = Ph, 4-MeC6H4, 2-thienyl, etc.; R1 = Ph, 2-naphthyl, 3-thienyl, etc.] and arylselanyl-aryl-oxazoles II [R2 = Ph, 2,4,6-triMeC6H2; R3 = CO2Et, Ph, 4-MeSC6H4, etc.] was disclosed. The established methodol. provided an efficient and practical pathway to access arylselenated heterocycles via copper-catalyzed double C-Se bond formation. This transformation featured the use of elemental Se as the selenating reagent, a cost-effective catalytic system and the late-stage selenation of bioactive compounds
After consulting a lot of data, we found that this compound(118994-89-1)Name: Ethyl oxazole-5-carboxylate can be used in many types of reactions. And in most cases, this compound has more advantages.