Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 118994-89-1, is researched, SMILESS is O=C(C1=CN=CO1)OCC, Molecular C6H7NO3Journal, Article, Research Support, Non-U.S. Gov’t, Organic Letters called Direct arylation of oxazoles at C2. a concise approach to consecutively linked oxazoles, Author is Flegeau, Emmanuel Ferrer; Popkin, Matthew E.; Greaney, Michael F., the main research direction is substituted oxazole derivative preparation; oxazole aryl iodide cross coupling palladium; teroxazolecarboxylate preparation.COA of Formula: C6H7NO3.
The synthesis of bis- and trisoxazoles via direct arylation is discussed. A variety of aryl groups can be installed at the 2-position of 5-aryl and 5-carboxy-substituted oxazoles under mild conditions using palladium catalysis on water. The direct arylation method can be extended to the synthesis of bis- and trisoxazoles if 2-triisopropylsilyl-4-iodooxazole is used as the electrophile in the arylation.
After consulting a lot of data, we found that this compound(118994-89-1)COA of Formula: C6H7NO3 can be used in many types of reactions. And in most cases, this compound has more advantages.