The effect of the change of synthetic route on the product 118994-89-1

After consulting a lot of data, we found that this compound(118994-89-1)Name: Ethyl oxazole-5-carboxylate can be used in many types of reactions. And in most cases, this compound has more advantages.

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Ethyl oxazole-5-carboxylate( cas:118994-89-1 ) is researched.Name: Ethyl oxazole-5-carboxylate.Li, Chengliang; Li, Pinhua; Yang, Jin; Wang, Lei published the article 《Palladium-catalyzed deamidative arylation of azoles with arylamides through a tandem decarbonylation-C-H functionalization》 about this compound( cas:118994-89-1 ) in Chemical Communications (Cambridge, United Kingdom). Keywords: azole arylamide palladium chemoselective regioselective deamidative arylation; aryl azole preparation; chemoselective regioselective deamidative arylation catalyst palladium. Let’s learn more about this compound (cas:118994-89-1).

A highly chemo-, regio-selective, and efficient palladium-catalyzed deamidative arylation of azoles with arylamides, as an aryl metal equivalent, has been developed. The reaction proceeds smoothly to generate the corresponding products in good yields via a tandem decarbonylation-C-H activation.

After consulting a lot of data, we found that this compound(118994-89-1)Name: Ethyl oxazole-5-carboxylate can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem