Application In Synthesis of Ethyl oxazole-5-carboxylate. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Ethyl oxazole-5-carboxylate, is researched, Molecular C6H7NO3, CAS is 118994-89-1, about Nickel-catalyzed decarboxylative acylation of heteroarenes by sp2 C-H functionalization. Author is Yang, Ke; Zhang, Cheng; Wang, Peng; Zhang, Yan; Ge, Haibo.
Nickel-catalyzed ligand-free decarboxylative cross-coupling of azole derivatives with α-oxoglyoxylic acids was developed. This work represents the first example of decarboxylative cross-coupling reactions, in a C-H bond functionalization manner, through nickel catalysis, and tolerates various functional groups. Addnl., this approach provides an efficient access to (ox)azole ketones, an important structural motif in many medicinal compounds with a broad range of biol. activities. © 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Although many compounds look similar to this compound(118994-89-1)Application In Synthesis of Ethyl oxazole-5-carboxylate, numerous studies have shown that this compound(SMILES:O=C(C1=CN=CO1)OCC), has unique advantages. If you want to know more about similar compounds, you can read my other articles.