The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Ethyl oxazole-5-carboxylate, is researched, Molecular C6H7NO3, CAS is 118994-89-1, about Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate, the main research direction is direct amidation azole formamide reactant azolecarboxamide preparation; tertbutyl perbenzoate oxidant amidation azole formamide reactant; cross coupling azolecarboxamide preparation tertbutyl perbenzoate oxidant.SDS of cas: 118994-89-1.
A novel and simple method for the direct amidation of azoles with formamides has been developed. The reaction could occur smoothly in the presence of tert-Bu perbenzoate (TBPB) as an oxidant under metal- and base-free conditions. Direct dehydrogenative cross-coupling of formamides and azoles generated the corresponding products, e.g. I (X = S, R = Me2N, EtNH; X = O, R = 2-MeC6H4NH, Et2N), in good yields.
After consulting a lot of data, we found that this compound(118994-89-1)SDS of cas: 118994-89-1 can be used in many types of reactions. And in most cases, this compound has more advantages.