Quality Control of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid, is researched, Molecular C4H6N2O2S, CAS is 2150-55-2, about Enzymatic characteristics in the bioconversion of D,L-ATC to L-cysteine. Author is Ryu, Ok Hee; Shin, Chul Soo.
The bioconversion of DL-2-aminothiazoline-4-carboxylic acid (I) to L-cysteine (II) was investigated. After the intracellular enzyme of a Pseudomonas species was inducibly formed by addition of I in the middle of culture, the cells were isolated and treated with sonication to prepare the crude enzyme solution I was the only isomeric form of the amino acid produced from I and its production could be enhanced several 10-fold by addition of Mn2+ which was required as a cofactor in the enzymic reaction. In addition, this reaction suffered from feedback inhibition of II. On the other hand, since a II-decomposing enzyme coexisted in the crude enzyme solution, most of the II formed disappeared in the absence of its inhibitor. However, hydroxylamine was a potent inhibitor which could successfully prevent the decomposition of II.
Although many compounds look similar to this compound(2150-55-2)Quality Control of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid, numerous studies have shown that this compound(SMILES:O=C(C1N=C(N)SC1)O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.