Flexible application of in synthetic route 91912-53-7

Compounds in my other articles are similar to this one(3-(Pyridin-4-yl)-1H-pyrazol-5-amine)Formula: C8H8N4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Design and Synthesis of the Potent, Orally Available, Brain-Penetrable Arylpyrazole Class of Neuropeptide Y5 Receptor Antagonists, published in 2003-02-27, which mentions a compound: 91912-53-7, mainly applied to indancarboxamide arylpyrazolyl preparation neuropeptide Y5 receptor antagonist, Formula: C8H8N4.

Novel arylpyrazole derivatives were synthesized and evaluated as neuropeptide Y5 receptor antagonists. The 2,3-dihydro-1H-cyclopenta[a]naphthalene derivative I showed good binding affinity and antagonistic activity for the Y5 receptor. After intracerebroventricular administration in SD rats, (-)-I significantly inhibited food intake that was induced by the centrally administered Y5-preferring agonist, bovine pancreatic polypeptide, but had only a negligible effect on NPY-induced feeding.

Compounds in my other articles are similar to this one(3-(Pyridin-4-yl)-1H-pyrazol-5-amine)Formula: C8H8N4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem