In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and hypoxia-selective cytotoxicity of a 2-nitroimidazole mustard, published in 1998-07-07, which mentions a compound: 121816-79-3, mainly applied to chloroethylaminonitroimidazole preparation hypoxia selective cytotoxicity; nitroimidazole mustard preparation hypoxia selective cytotoxicity; imidazole chloroethylaminonitro preparation hypoxia selective cytotoxicity, Product Details of 121816-79-3.
A four-step synthesis of 5-[N,N-bis(2-chloroethyl)amino]-1-methyl-2-nitroimidazole from 1-methyl-2-nitroimidazole is described. This compound showed similar hypoxia-selective cytotoxicity to the dinitrobenzamide mustard SN 23862 in UV4 cells (ca. 40-fold), and superior selectivity (>7-fold) in repair-competent AA8 cells.
In some applications, this compound(121816-79-3)Product Details of 121816-79-3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.