Huai, Lihua; Chen, Ning; Yang, Wenbo; Bai, Gang published the article 《Metabolic control analysis of L-cysteine producing strain TS1138 of Pseudomonas sp》. Keywords: model cysteine Pseudomonas metabolic control analysis.They researched the compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid( cas:2150-55-2 ).Application In Synthesis of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:2150-55-2) here.
A kinetic model describing the biosynthesis of L-cysteine by Pseudomonas sp. TS1138 has been developed. The two enzymes catalyzing this pathway, L-cysteine synthetase (CS) and L-cysteine desulfhydrase (CD), follow Michaelis-Menten kinetics with noncompetitive inhibition of CS by L-cysteine. From measurements of intermediates and end products that were made during L-cysteine enzymic synthesis, metabolic control anal. of the pathway was carried out using the kinetic model. The elasticity coefficients and the flux control coefficients were calculated, and the anal. revealed a shift in the flux control from CS to CD during the reaction. The findings further implicate potential targets and strategies for increasing L-cysteine production; for example, the strain TS1138 could be manipulated by site-directed mutagenesis to reduce CD activity.
As far as I know, this compound(2150-55-2)Application In Synthesis of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.