Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 2150-55-2, is researched, SMILESS is O=C(C1N=C(N)SC1)O, Molecular C4H6N2O2SJournal, Article, Bioscience, Biotechnology, and Biochemistry called N-carbamoyl-L-cysteine as an intermediate in the bioconversion from D,L-2-amino-Δ2-thiazoline-4-carboxylic acid to L-cysteine by Pseudomonas sp. ON-4a, Author is Tamura, Yoshiharu; Nishino, Mizuka; Ohmachi, Tetsuo; Asada, Yoshihiro, the main research direction is Pseudomonas carbamoylcysteine; 2-amino-Δ 2-thiazoline-4-carboxylic acid (ATC); L-cysteine; N-carbamoyl-L-cysteine (L-NCC); Pseudomonas species; bioconversion.Quality Control of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid.
The authors investigated the conversion of D,L-2-amino-Δ2-thiazoline-4-carboxylic (D,L-ATC) to L-cysteine with Pseudomonas sp. ON-4a, an ATC-assimilating bacterium. Cysteine and N-carbamoylcysteine (NCC), but not S-carbamoylcysteine (SCC), were produced from D,L-ATC by a cell-free extract from the strain. These products were isolated from the reaction mixture and then identified as the L-form. Similar results were obtained with P. putida AJ3865 and unidentified strain TG-3, an ATC-assimilating bacteria. It became clear that L-NCC is an intermediate in the conversion of D,L-ATC to L-cysteine in these Pseudomonas strains. Furthermore, it was suggested that these bacteria have L-ATC hydrolase and L-NCC amidohydrolase.
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