Munoz, Juan de M.; Alcazar, Jesus; de la Hoz, Antonio; Diaz-Ortiz, Angel published an article about the compound: Ethyl oxazole-5-carboxylate( cas:118994-89-1,SMILESS:O=C(C1=CN=CO1)OCC ).Recommanded Product: Ethyl oxazole-5-carboxylate. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:118994-89-1) through the article.
The reduction of esters to aldehydes is an important transformation in organic chem. and several reducing agents have been described. However, the use of this reaction in medicinal and natural product chem. is limited due to the instability of the intermediates and the high reactivity of the reaction products. In the current article, the general and selective reduction of esters with lithium diisobutyl-tert-butoxyaluminum hydride (LDBBA) in flow is reported. This reagent allows esters to be reduced in the presence of different functional groups, including those considered to be of similar or higher reactivity.
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