In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Continuous flow as an enabling technology: a fast and versatile entry to functionalized glyoxal derivatives, published in 2021, which mentions a compound: 118994-89-1, mainly applied to glyoxal preparation; dichloromethane ester condensation continuous flow; ethyl diethoxyacetate aryl bromide condensation continuous flow; bromochlorobenzene ester condensation continuous flow, Name: Ethyl oxazole-5-carboxylate.
Two complementary strategies employing organolithium chem. for the synthesis of glyoxal derivatives RC(O)R1R2 (R = methoxymethyl, 3,5-difluorophenyl, pyridin-2-yl, quinolin-6-yl, etc.; R1 = Cl, OEt, H; R2 = Cl, OEt, 3-chlorophenyl) were reported. Micro-mixer technol. allows for the generation of unstable organometallic intermediates and their instantaneous in-line quenching with esters as electrophiles RC(O)OEt. Selective mono-addition was observed via putative stabilized tetrahedral intermediates. Advantages offered by flow chem. technologies facilitate direct and efficient access to masked 1,2-dicarbonyl compounds while mitigating undesired byproduct formation. These two approaches enable the production of advanced and valuable synthetic building blocks for heterocyclic chem. with throughputs of grams per min.
From this literature《Continuous flow as an enabling technology: a fast and versatile entry to functionalized glyoxal derivatives》,we know some information about this compound(118994-89-1)Name: Ethyl oxazole-5-carboxylate, but this is not all information, there are many literatures related to this compound(118994-89-1).