Reference of 5-Amino-2-fluoropyridine. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 5-Amino-2-fluoropyridine, is researched, Molecular C5H5FN2, CAS is 1827-27-6, about Sulfonamide Synthesis via Calcium Triflimide Activation of Sulfonyl Fluorides.
A method using calcium triflimide [Ca(NTf2)2] as a Lewis acid to activate sulfonyl fluorides toward nucleophilic addition with amines is described. The reaction converts a wide array of sterically and electronically diverse sulfonyl fluorides and amines into the corresponding sulfonamides in good yield.
This literature about this compound(1827-27-6)Reference of 5-Amino-2-fluoropyridinehas given us a lot of inspiration, and I hope that the research on this compound(5-Amino-2-fluoropyridine) can be further advanced. Maybe we can get more compounds in a similar way.