Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 118994-89-1, is researched, Molecular C6H7NO3, about Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate, the main research direction is direct amidation azole formamide reactant azolecarboxamide preparation; tertbutyl perbenzoate oxidant amidation azole formamide reactant; cross coupling azolecarboxamide preparation tertbutyl perbenzoate oxidant.Recommanded Product: Ethyl oxazole-5-carboxylate.
A novel and simple method for the direct amidation of azoles with formamides has been developed. The reaction could occur smoothly in the presence of tert-Bu perbenzoate (TBPB) as an oxidant under metal- and base-free conditions. Direct dehydrogenative cross-coupling of formamides and azoles generated the corresponding products, e.g. I (X = S, R = Me2N, EtNH; X = O, R = 2-MeC6H4NH, Et2N), in good yields.
This literature about this compound(118994-89-1)Recommanded Product: Ethyl oxazole-5-carboxylatehas given us a lot of inspiration, and I hope that the research on this compound(Ethyl oxazole-5-carboxylate) can be further advanced. Maybe we can get more compounds in a similar way.