The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid, is researched, Molecular C4H6N2O2S, CAS is 2150-55-2, about The potential use of 2-aminothiazoline-4-carboxylic acid (ATCA) as a forensic marker for cyanide exposure in medicolegal death investigation: A review., the main research direction is 2-Aminothiazoline-4-carboxylic acid; biomarkers; cyanide exposure; cyanide poisoning; death investigation; forensic markers; forensic science.Application of 2150-55-2.
Cyanide (CN) is one of the most toxic of all substances and can be found in various natural and anthropogenic sources. Sensitive and effective methods for the confirmation of CN exposure are crucial in medical, military, and forensic settings. Due to its high volatility and reactivity, direct detection of CN from postmortem samples could raise inconclusive interpretation issues that may hinder accurate determination of the cause of death. The detection of the alternative CN metabolites as markers to test CN exposure may offer a solution to reduce the potential for false-negative and false-positive results. 2-Aminothiazoline-4-carboxylic acid (ATCA) is a minor metabolite of CN and has been proposed to be a potential alternative forensic marker for the confirmation of CN exposure. According to the current state of knowledge, ATCA has not yet been associated with other metabolic pathways except for CN detoxification. Moreover, ATCA is stable under various conditions over time. This article reviews analytical methods developed for the analysis of ATCA as well as studies related to potential use of ATCA as a marker for the diagnosis of CN exposure. The need for research related to the use of ATCA as a reliable forensic marker for CN exposure in medicolegal death investigations is also discussed.
If you want to learn more about this compound(2-Amino-4,5-dihydrothiazole-4-carboxylic acid)Application of 2150-55-2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(2150-55-2).