Month: February 2022

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 14508-49-7, Name is 2-Chloropyrazine, molecular formula is , belongs to pyrazines compound. In a document, author is Wu, Kun, Computed Properties of C4H3ClN2.

Herein, we report the synthesis of three pairs of isostructural zirconium- and hafnium-based homometallic metal-organic frameworks (MOFs, termed Zr-MOF-1 and Hf-MOF-1, Zr-MOF-2 and Hf-MOF-2, and Zr-MOF-3 and Hf-MOF-3) with respective scu, sqc, and flu topologies by using the aggregation-induced-emission (AIE) ligand H4BTTB (4,4 ‘,4 ”,4 ”’-(pyrazine-2,3,5,6-tetrayl)tetrabenzoic acid). As expected, all of them display excellent luminescence properties, and their potential application in the detection of Cr2O72- has been extensively studied. Among them, Zr/Hf-MOF-2 exhibits the high adsorption capacity for Cr2O72- (153 mg g(-1) and 149 mg g(-1), respectively), while Zr/Hf-MOF-3 demonstrates exceptional sensitivity in the detection of Cr2O72-, and the limits of detection are calculated to be 0.013 mu M and 0.019 mu M, respectively. The values are comparable to those of the best-performing MOF materials reported so far. Significantly, single-crystal X-ray diffraction studies revealed the exact location and configuration of Cr2O72- inside Zr/Hf-MOF-2. To the best of our knowledge, this is the first example of Zr/Hf-MOFs with direct evidence showing that Cr2O72- is linked to the Zr/Hf oxide cluster by replacing its terminal H2O/OH- groups within the single crystal.

If you are hungry for even more, make sure to check my other article about 14508-49-7, Computed Properties of C4H3ClN2.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 2847-30-5, Name is 2-Methoxy-3-methylpyrazine, molecular formula is C6H8N2O. In an article, author is Yu, You-Jun,once mentioned of 2847-30-5, Application In Synthesis of 2-Methoxy-3-methylpyrazine.

Derivatives based on anthryleno[1,2-b]pyrazine-2,3-dicarbonitrile (DCPA) are used as luminescent materials, to realize near-infrared (NIR) electroluminescence. By functionalizing DCPA with aromatic amine donors, two emitters named DCPA-TPA and DCPA-BBPA are designed and synthesized. Both molecules have large dipole moments owing to the strong intramolecular charge transfer interactions between the amine donors and the DCPA acceptor. Thus, compared with doped films, the emission of neat films of DCPA-TPA and DCPA-BBPA can fully fall into the NIR region (>700 nm) with increasing surrounding polarity by increasing doping ratio. Moreover, the non-doped devices based on DCPA-TPA and DCPA-BBPA provide NIR emission with peaks at 838 and 916 nm, respectively. A maximum radiance of 20707 mW Sr-1 m(-2) was realized for the further optimized device based on DCPA-TPA. This work provides a simple and efficient strategy of molecular design for developing NIR emitting materials.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 2847-30-5, you can contact me at any time and look forward to more communication. Application In Synthesis of 2-Methoxy-3-methylpyrazine.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Moghzi, Faezeh, once mentioned the application of 14508-49-7, Name is 2-Chloropyrazine, molecular formula is C4H3ClN2, molecular weight is 114.53, MDL number is MFCD00006124, category is pyrazines. Now introduce a scientific discovery about this category, COA of Formula: C4H3ClN2.

Four new praseodymium(III) metal-organic compounds varying in dimensionality from 0D to 3D have been designed and synthesized based on N-heterocyclic polycarboxylic acids, including pyridine-2,6-dicarboxylic acid (H(2)pydc) and pyrazine-2,3-dicarboxylic acid (H(2)pzdc). Altering the concentration of piperazine (pip, ancillary ligand) enables control over the dimensionality of the compound by switching between the 0D [H(2)pip][Hpip][Pr(pydc)(3)]center dot 4H(2)O (I) and the 1D {[Pr(pydc)( Hpydc)(H2O)(2)]center dot 4H(2)O}(n) (II) coordination polymer (CP). Upon replacing H(2)pydc with H2pzdc, CP II is converted to the 2D CP [Pr(pzdc)(Hpzdc)(H2O)(3)](n) (III) and using the metalloligand [Zn(Hpzdc)(2)(H2O)(2)](2-) the 3D heterometallic CP {[Pr2Zn(pzdc)(4)(H2O)(6)]center dot 2H(2)O}(n) (IV) is formed. Compound IV shows high stability in the absence of uncoordinated solvent molecules and is stable up to 400 degrees C, even in the presence of humidity. Therefore, IV was utilized for iodine adsorption in the vapour phase and in the presence of humidity. The results confirm the remarkable potential of IV for reversible adsorption of iodine vapour.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 14508-49-7, COA of Formula: C4H3ClN2.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 19847-12-2, Name is Pyrazinecarbonitrile. In a document, author is Elkamhawy, Ahmed, introducing its new discovery. Category: Pyrazines.

Herein, two new series ofN-substituted indole-based analogues were rationally designed, synthesizedviamicrowave heating technology, and evaluated as noteworthy MAO-B potential inhibitors. Compared to the reported indazole-based hitsVIandVII, compounds4band4eexhibited higher inhibitory activities over MAO-B with IC(50)values of 1.65 and 0.78 mu M, respectively. When compared to the modest selectivity index of rasagiline (II, a well-known MAO-B inhibitor, SI > 50), both4band4ealso showed better selectivity indices (SI > 60 and 120, respectively). A further kinetic evaluation of the most potent derivative (4e) displayed a competitive mode of inhibition (inhibition constant (K-i)/MAO-B = 94.52 nM). Reasonable explanations of the elicited biological activities were presentedviaSAR study and molecular docking simulation. Accordingly, the remarkable MAO-B inhibitory activity of4e(N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide), with its selectivity and competitive inhibition, advocates its potential role as a promising lead worthy of further optimization.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 19847-12-2 help many people in the next few years. Category: Pyrazines.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

Synthetic Route of 89-01-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to pyrazines compound. In a article, author is Tan, Yee Seng, introduce new discover of the category.

C20H38CdN4O4P2S4, triclinic, P (1) over bar (no. 2), a = 9.6352(2) angstrom, b = 11.3986(2) angstrom, c = 14.8017(3) angstrom, alpha = 85.713(2)degrees, beta = 89.877(2)degrees, gamma = 86.048(2)degrees, V = 1617.23(6) angstrom(3), Z = 2, R-gt(F) = 0.0285, wR(ref)(F-2) = 0.0829, T = 100 K.

Synthetic Route of 89-01-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 89-01-0.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

Reference of 89-01-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a article, author is Tan, Yee Seng, introduce new discover of the category.

C20H38CdN4O4P2S4, triclinic, P (1) over bar (no. 2), a = 9.6352(2) angstrom, b = 11.3986(2) angstrom, c = 14.8017(3) angstrom, alpha = 85.713(2)degrees, beta = 89.877(2)degrees, gamma = 86.048(2)degrees, V = 1617.23(6) angstrom(3), Z = 2, R-gt(F) = 0.0285, wR(ref)(F-2) = 0.0829, T = 100 K.

Reference of 89-01-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 89-01-0.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

Formula: C5H4N2O2. I found the field of Chemistry very interesting. Saw the article Pd(II)-catalyzed, Picolinamide-aided sp(2) gamma-C-H Functionalization of Phenylglycinol: Access to gamma-C-H Arylated, Alkylated and Halogenated Phenylglycinol Scaffolds published in 2021, Reprint Addresses Babu, SA (corresponding author), Indian Inst Sci Educ & Res IISER Mohali, Dept Chem Sci, Sect 81, Manauli Po 140306, Punjab, India.. The CAS is 98-97-5. Through research, I have a further understanding and discovery of Pyrazine-2-carboxylic acid.

We report the Pd(II)-catalyzed picolinamide-aided ortho-C-H arylation-, alkylation-, and halogenation (sp(2) gamma-C-H functionalization) of phenylglycinol substrates. Phenylglycinols are remarkable building blocks and have found different applications in synthetic organic and medicinal chemistry. This work is a contribution towards the expansion of the library of phenylglycinol scaffolds and also substrate scope development by using the Pd(II)-catalyzed bidentate directing group picolinamide-aided C-H activation tactic.

Bye, fridends, I hope you can learn more about C5H4N2O2, If you have any questions, you can browse other blog as well. See you lster.. Formula: C5H4N2O2

Reference:
Patent; Chevron Research Company; US4732894; (1988); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Category: Pyrazines. I found the field of Chemistry very interesting. Saw the article Pantoprazole Derivatives: Synthesis, Urease Inhibition Assay and In Silico Molecular Modeling Studies published in 2020, Reprint Addresses Balalaie, S (corresponding author), KN Toosi Univ Technol, Peptide Chem Res Ctr, POB 15875-4416, Tehran, Iran.; Balalaie, S (corresponding author), Kermanshah Univ Med Sci, Med Biol Res Ctr, Kermanshah, Iran.. The CAS is 98-97-5. Through research, I have a further understanding and discovery of Pyrazine-2-carboxylic acid.

A number of pantoprazole derivatives were synthesized and screened for their urease inhibitory properties. Some of them showed potent inhibitions against jack bean urease. All compounds showed varying degree of IC50 in the range of 25.85 to 181 mu Mol as compared to standard acetohydroxamic acid (AHA) (100 +/- 2.02 mu Mol). Derivatives bearing 5-aryl-1,3,4-oxadiazole ring substitutions (aryl= pyrazyl, pyridyl and phenyl) were found to be more potent inhibitors than AHA and pantoprazole. The most promising compound, 2-((3,4-dimethoxypyridin-2-yl)methylthio)-5-(pyrazin-2-yl)-1,3,4-oxadiazole 12, with IC50 value of 25.85 +/- 1.21 showed remarkable urease inhibition activity. In silico molecular modeling investigation performed to rationalize the possible binding interaction and ADME properties of compounds over the active site of urease enzyme. The induced fit docking study showed that compound 12 interacted with conserved residues His593 and Arg609 located at the mouth of the urease active site flap and are essential for enzyme catalytic activity. These target compounds could be further studied as a lead skeleton for discovery of novel urease inhibitors.

Welcome to talk about 98-97-5, If you have any questions, you can contact Azizian, H; Esmailnejad, A; Vavsari, VF; Mahernia, S; Amanlou, M; Balalaie, S or send Email.. Category: Pyrazines

Reference:
Patent; Chevron Research Company; US4732894; (1988); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Safety of Pyrazine-2-carboxylic acid. I found the field of Chemistry very interesting. Saw the article Palladium-Catalyzed Regioselective C-H Iodination of Unactivated Alkenes published in 2019, Reprint Addresses Carreira, EM (corresponding author), Swiss Fed Inst Technol, HCI, Vladimir Prelog Weg 3, CH-8093 Zurich, Switzerland.. The CAS is 98-97-5. Through research, I have a further understanding and discovery of Pyrazine-2-carboxylic acid.

A palladium-catalyzed C-H iodination of unactivated alkenes is reported. A picolinamide directing group enables the regioselective functionalization of a wide array of olefins to furnish iodination products as single stereoisomers. Mechanistic investigations suggest the reversible formation of a six-membered alkenyl palladacycle intermediate through a turnover-limiting C-H activation.

Safety of Pyrazine-2-carboxylic acid. Bye, fridends, I hope you can learn more about C5H4N2O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Patent; Chevron Research Company; US4732894; (1988); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Recommanded Product: 98-97-5. I found the field of Chemistry very interesting. Saw the article Cobalt-Catalyzed Direct Carbonylative Synthesis of Free (NH)-Benzo[cd]indol-2(1H)-ones from Naphthylamides published in 2019, Reprint Addresses Wu, XF (corresponding author), Zhejiang Sci Tech Univ, Dept Chem, Xiasha Campus, Hangzhou 310018, Peoples R China.; Wu, XF (corresponding author), Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany.. The CAS is 98-97-5. Through research, I have a further understanding and discovery of Pyrazine-2-carboxylic acid.

A cobalt-catalyzed C-H carbonylation of naphthylamides for the synthesis of benzo[cd]indol-2(1H)-one scaffolds has been developed. The reaction employs a traceless directing group and uses benzene-1,3,5-triyltriormate as the CO source, affording various free (NH)-benzo[cd]indol-2(1H)-ones in moderate to high yields (up to 88%). Using this protocol, the total synthesis of BET bromodomain inhibitors A and B was accomplished as well.

Recommanded Product: 98-97-5. About Pyrazine-2-carboxylic acid, If you have any questions, you can contact Ying, J; Fu, LY; Zhong, GQ; Wu, XF or concate me.

Reference:
Patent; Chevron Research Company; US4732894; (1988); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem