Authors Priyanka; Neelabh; Tiwari, N; Sharma, RK; Gupta, P; Misra, S; Misra-Bhattacharya, S; Butcher, RJ; Singh, K; Katiyar, D in WILEY-V C H VERLAG GMBH published article about PARASITIC NEMATODE; CHITINASE; COUMARINS; DRUG in [Priyanka; Tiwari, Neha; Sharma, Rajesh K.; Katiyar, Diksha] Banaras Hindu Univ, Dept Chem, MMV, Varanasi 221005, Uttar Pradesh, India; [Neelabh; Singh, Karuna] Banaras Hindu Univ, Dept Zool, MMV, Varanasi 221005, Uttar Pradesh, India; [Gupta, Poonam] Mahanand Miss Harijan Coll, Dept Chem, Ghaziabad 201001, India; [Misra, Sweta; Misra-Bhattacharya, Shailja] CSIR, Cent Drug Res Inst, Div Parasitol, BS 10-1,Sitapur Rd, Lucknow 226031, Uttar Pradesh, India; [Butcher, Ray J.] Howard Univ, Dept Chem, 525 Coll St NW, Washington, DC 20059 USA in 2019, Cited 28. Quality Control of Pyrazine-2-carboxylic acid. The Name is Pyrazine-2-carboxylic acid. Through research, I have a further understanding and discovery of 98-97-5
A series of 7-benzamidocoumarin derivatives 10-25 starting from 7-amino coumarins 7 and 8 has been synthesized, characterized and evaluated in vitro for antifilarial activity against the human lymphatic filarial parasite, Brugia malayi. Compounds 13 and 20-23 showed permanent paralysis of the worm with 90-95% inhibition of motility of adult worms at 10 mu M. All the synthesized compounds were docked on the modeled receptor of Onchocerca volvulus chitinase OvCHT1. Compound 13 with binding energy of -7.95 Kcal/mol showing three hydrogen bonds with the active site of the enzyme emerged as the best inhibitor.
Quality Control of Pyrazine-2-carboxylic acid. About Pyrazine-2-carboxylic acid, If you have any questions, you can contact Priyanka; Neelabh; Tiwari, N; Sharma, RK; Gupta, P; Misra, S; Misra-Bhattacharya, S; Butcher, RJ; Singh, K; Katiyar, D or concate me.
Reference:
Patent; Chevron Research Company; US4732894; (1988); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem