Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1320266-90-7, name is 8-Chloro-3-isopropylimidazo[1,5-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 1320266-90-7
To a solution of 8-chloro-3-isopropylimidazo[1,5-ajpyrazine 3A (1.00 g, 5.11 mmol) in THFat -65 C was added dropwise a solution of n-butyllithium (2.5 M solution in THF, 2.9 mL,7.16 mmol), keeping the temperature below -55 C. The resulting dark brown solution was stirred at -78 C for 1 h then ethyl formate (0.62 mL, 7.67 mmol) was added dropwise and the mixture was stirred at -78 C for 1.5 h. The mixture was diluted with water and extracted with EtOAc. The combined organic extracts were dried (MgSO4), filtered and concentrated invacuo. The residue was purified by silica-gel chromatography, eluting with 0-50% EtOAc in isohexane to give the title compound 3B as a yellow oil that crystallised on standing (900 mg, 79%). LC-MS (Method 1): Rt = 1.06 mm, m/z = 224.1 [M(35C1)+Hf?.
According to the analysis of related databases, 1320266-90-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; OPTIKIRA LLC; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; KEENAN, Richard M.; BACKES, Bradley J.; MALY, Dustin J.; REYNOLDS, Charles; WHITTAKER, Ben; KNIGHT, Jamie; SUTTON, Jon; HYND, George; PAPA, Feroz, R.; OAKES, Scott, A.; (147 pag.)WO2019/46711; (2019); A2;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem