Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 54013-07-9, name is 5-Methoxypyrazin-2-amine, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 5-Methoxypyrazin-2-amine
To a solution of 5-amino-3,4-dimethylisoxazole (2.00 g, 17.8 mmol, 1.0 equiv; CASNo. 19947-75-2) in THF (180 mL) at 0 C was added pyridine (1.80 mL, 22.3 mmol, 1.25 equiv) followed by phenyl chloroformate (2.36 mL, 18.7 mmol, 1.05 equiv). After stirring at 00C for 2.5 h, the reaction was warmed to room temp overnight. The reaction was diluted with ethyl acetate and washed with 2M HCI, water, saturated sodium bicarbonate, and brine. The organic layer was dried over magnesium sulfate, filtered, concentrated, and 10 purified by flash chromatography (dichloromethane/hexane) to give the title compound as a white solid (2.33 g). 1H NMR (400 MHz, DMSO-Cf6) delta ppm 10.70 (br. s., 1 H), 7.40 – 7.47 (m, 2 H), 7.26 – 7.30 (m, 1 H), 7.21 – 7.25 (m, 2 H), 2.16 (s, 3 H), 1.86 (s, 3 H). m/z 233 (MH+).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 54013-07-9.
Reference:
Patent; PFIZER INC.; WO2009/127944; (2009); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem