Application of 27398-39-6, The chemical industry reduces the impact on the environment during synthesis 27398-39-6, name is 3-Chloropyrazine-2-carboxylic acid, I believe this compound will play a more active role in future production and life.
3-chloropyrazine-2-carboxylic acid (1.59 g, 10 mmol) was dissolved in dichlorosulfoxide (10 mL)DMF (0.5 mL) was added dropwise, 90 C for 2 hours. Reaction is completed, The solvent is evaporated to dryness, Ice bath, The oily product was slowly added dropwise to absolute ethanol (20 mL) After stirring at room temperature for 1 hour, The solvent was concentrated to dryness, To give the title compound (1.7 g, yield 91.1%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Chloropyrazine-2-carboxylic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Shandong Xuanzhu Pharmaceutical Co., Ltd.; Wu, Yongqian; (31 pag.)CN106317027; (2017); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem