In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 63744-22-9 as follows. Recommanded Product: 63744-22-9
Intermediate Example 16-Bromo-8-(methylsulfanyl)imidazo 1 ,2-a]pyrazineA mixture of 61 .0 g (220 mmol) 6,8-dibromoimidazo[1 ,2-a]pyrazine (CAS 63744- 22-9), 610 mL methanol and 30.2 g sodium methanethiolate was stirred at 23 C for 16 hours, poured into 6 L water and cooled until a precipitate had formed. The product was filtered off and dried at 60C to give 38.5 g (72%) of the title compound which was used without further purification.
According to the analysis of related databases, 63744-22-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; KLAR, Ulrich; KOPPITZ, Marcus; KOSEMUND, Dirk; BOHLMANN, Rolf; BADER, Benjamin; LIENAU, Philip; SIEMEISTER, Gerhard; PRECHTL, Stefan; NGUYEN, Duy; SCOTT, William; WO2011/113862; (2011); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem