Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 957344-74-0, name is 5,8-Dibromoimidazo[1,2-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., Safety of 5,8-Dibromoimidazo[1,2-a]pyrazine
Step 3 (5-Bromo-imidazo[l,2-a]pyrazin-8-yl)-[6-(4-isopropyl-piperazin-l-yl)-pyridin-3-yl] -amine[00410] To a solution of 5,8-dibromo-imidazo[l,2-a]pyrazme (0 85g, 3 lmmol) in isopropanol are added 6-(4-isopropyl-piperazin-l-yl)-pyridm-3-yl-amme (0 68g, 3 lmmol) and dnsopropylethylamme (0 6mL, 4 6mmol) and the mixture is stirred at 900C for 48 hours The solvent is removed in vacuo and the product taken up in DCM-10% cit?c acid The organic layer is discarded and the aqueous solution basified with sat NaHCO3 (pH 7-8) and extracted using DCM The organic layer is d?ed over MgSO4, filtered and concentrated in vacuo to afford the title compound as a purple solid (0 92g, 71%) HPLC (254nm) Rt 3 30mm (95 8%), m/z 416/418 (M+H)+
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 957344-74-0.
Reference:
Patent; GALAPAGOS N.V.; WO2007/131991; (2007); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem