Adding a certain compound to certain chemical reactions, such as: 75907-74-3, name is (3,5,6-Trimethylpyrazin-2-yl)methanol, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 75907-74-3, name: (3,5,6-Trimethylpyrazin-2-yl)methanol
To a solution of (3,5,6-trimethylpyrazin-2-yl)methanol(4) (15.50 g, 102 mmol) in anhydrous CH2Cl2 (300 mL),thionyl chloride (7.41 mL, 102 mmol) was added drop bydrop at 0 C. After finishing dropping, the mixture wasstirred at room temperature for 2.5 h. The solvent was evaporatedin vacuo and the product 2-chloromethyl-3,5,6-trimethylpyrazine hydrochloride (5) was obtained as yellowsolid (21.11 g, 100%), mp: 102-105 C [11].
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Reference:
Article; Li, Zhenyu; Yu, Fang; Cui, Lei; Chen, Wenmin; Wang, Shouxun; Zhan, Peng; Shen, Yuemao; Liu, Xinyong; Medicinal Chemistry; vol. 10; 1; (2014); p. 81 – 89;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem