Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 762240-92-6, name is 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C6H8ClF3N4
(3R)-3-azido-4-(2,4,5-trifluorophenyl)-buryric acid (5 g) obtained in step 3 and triazole derivative of formula (VI) (5.3 g) were added to DMF (40 ml) and water (20 ml), stirred for 15 min, and cooled to 10C . N- methylmorpholine (2.4 ml) was added to the mixture, stirred for 10 min, and cooled to 0 C . EDC (5.6 g) was added to the resulting mixture, and stirred for 1 hour. Ethyl acetate (50 ml) and water (25 ml) were added to the resulting mixture, and the organic layer formed thereafter was separated. The separated organic layer was washed four times with 50 ml of satuated saline, dried over MgSO4, and filtered. The organic solvent was removed from the filtrate under a reduced pressure to obtain the title compound (7.8 g; yield: 93%).1H-NMR(300MHz, CDC13): delta 7.20-7.11 (1H, m), 6.99-6.90 (1H, m), 5.20-4.96 (2H, m), 4.28-4.05 (5H, m), 2.98-2.67 (4H, m).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 762240-92-6.
Reference:
Patent; HANMI HOLDINGS CO., LTD.; KIM, Nam Du; CHANG, Ji Yeon; KIM, Dong Jun; LEE, Hyun Seung; JUNG, Jae Hyuk; CHANG, Young Kil; LEE, Gwan Sun; WO2011/49344; (2011); A2;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem